pioglitazone (pg) is one of thiazolidinediones used for the treatment of type ii diabetes mellitus. some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. in the present study, the protective effect of some atp suppliers are investigated against mitochondrial toxicity of pg in isolated rat mitochondria. mitochondrial viability was investigated by mt...

Pioglitazone (PG) is one of thiazolidinediones used for the treatment of type II diabetes mellitus. Some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. In the present study, the protective effect of some ATP suppliers are investigated against mitochondrial toxicity of PG in isolated rat mitochondria. Mitochondrial viability was investigated by MT...

Pioglitazone (PG) is one of thiazolidinediones used for the treatment of type II diabetes mellitus. Some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. In the present study, the protective effect of some ATP suppliers are investigated against mitochondrial toxicity of PG in isolated rat mitochondria. Mitochondrial viability was investigated by MT...

BACKGROUND & OBJECTIVES Phosphides used as an insecticide and rodenticide, produce phosphine (PH3) which causes accidental and intentional poisoning cases and deaths. There is no specific treatment or antidote available for PH3poisoning. It is suggested that PH3-induced toxicity is associated with adenosine triphosphate (ATP) depletion; therefore, in this study the effect of some nutrients was ...

Pioglitazone (PG) is one of thiazolidinediones used for the treatment of type II diabetes mellitus. Some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. In the present study, the protective effect of some ATP suppliers are investigated against mitochondrial toxicity of PG in isolated rat mitochondria. Mitochondrial viability was investigated by MT...

Acknowledgements I would like to thank the various company managers who participated in the surveys of Yorkshire & Humberside and Northern Ireland. Abstract Multinational enterprises occupy a prominent position in most UK regional economies. The contribution of these firms to employment and growth in the host region will be enhanced if they purchase material inputs from local firms ('local sour...

⎯In this study, two (or more) supply chains where the suppliers share information on their production, inventory and delivery status are considered. Due to uncertain supplier deliveries and lead time, horizontal supplier coordination is implemented to reduce lead time and deliveries uncertainty, and thus the safety inventory due to risk pooling effect. As a result, the total system profit incre...

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one of the most important issues in supply chain management in different companies, including automotive part manufacturing companies, is evaluation and selection of suppliers. this action is depended on quality management system requirements that must be based on performance and actual ability of suppliers. the analytic hierarchy process (ahp) is one of the most widely used method in the field...

According to the concept of green supply chain, in this paper, we introduce a multi-method multiple criteria approach to develope more appropriate green supplier programs and practices. In reality, investigation into this field of study has just begun. We propose a combination of new fuzzy clustering means (FCM) better than the traditional clustering method and technique for order of preference...